Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase that is closely related to Akt. SGK is rapidly induced in response to a variety of stimuli,including serum,hormones,and osmotic shock,etc. SGK has been involved in modulating anti-apoptotic and cell cycle regulation,as well as in activating certain potassium,sodium and chloride channels.
应用类型
Western blotting (0.5-4 ug/ml), immunoprecipitation (10-20 ug/ml). However, the optimal conditions should be determined individually. The antibody detects SGK from samples of human, mouse, and rat origins.
免疫原
Synthetic peptide corresponding to the C-terminus of human SGK
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的SGK蛋白发生免疫反应.
保存建议
提供的SGK抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该SGK抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.