Phospho-p38 MAPK Antibody,p38MAPK,p38-MAPK,p38 Mitogen Activated Protein Kinase,Mxi2,MAX-interacting protein 2,CSBP1,CSBP2,CSPB1,Csaids ,APK2A,stress-activated protein kinase 2A,p
p38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in ancascade controlling cellular responses to cytokines and stress. Like the SAPK/JNK pathway,np38 MAP kinase is activated by a variety of cellular stresses including inflammatory cytokines,nUV light and growth factors,etc. Activated p38 MAP kinase has been shown to phosphorylatenand activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.
应用类型
Western blotting (0.5-4 ug/ml), immunoprecipitation (10-20 mg/ml) and Immunohistochemistry (10-20 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 43 kDa phosphorylated p38 (Thr180/Tyr182) MAP kinase of human,nmouse, and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic phospho-peptide surrounding amino acid Thr180/Tyr182 of human p38 MAP kinase
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的Phospho-p38 MAPK蛋白发生免疫反应.
保存建议
提供的Phospho-p38 MAPK抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有50%甘油, 1% BSA和0.02%硫柳汞n的PBS缓冲液中.请将该Phospho-p38 MAPK抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.