Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. The family contains NCAM (for neuronal cell adhesion molecule),ICAM (for intercellular adhesion molecule),VCAM (vascular cell adhesion molecule),PECAM-1 (platelet/endothelial cell adhesion molecule-1),etc. ICAM-1,also referred to as CD54,is an integral membrane protein of the immunoglobulin superfamily and recognizes the B2a1 and B2aM integrins.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~89-92 kDa ICAM-1 in samples from human, mouse and rat origins.
免疫原
Synthetic peptide surrounding amino acid 359 of human CXCR5
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的ICAM-1蛋白发生免疫反应.
保存建议
提供的ICAM-1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该ICAM-1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.