Chemokines play an important role in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups,CXCR and CCR,based on the 2 major classes of chemokines. CXCR5 is one of the CXCR receptors,which is expressed in a variety of cells.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 36 kDa CXCR5 of human origin. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 359 of human CXCR5
来源宿主
兔
反应性
经检测验证,可与人种属来源的CXCR5蛋白发生免疫反应.
保存建议
提供的CXCR5抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该CXCR5抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.