It has been proposed that high density lipoproteins （HDLs） function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions，it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Jurkat cell lysate （Cat.# 2401-100） and mouse small intestine tissue Lysate （Cat.# 2601-100） can be used as positive controls. The antibody recognizes 70 kDa CETP of human & rat origins.
免疫原
Synthetic peptide corresponding to the C-terminus of human CETP
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠、兔种属来源的CETP蛋白 发生免疫反应.
保存建议
提供的CETP抗体 产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该CETP抗体 产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
