Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B,H,K,L,O,and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis,protein degradation,and apoptosis. Cathepsin K expression is highest in bone,cartilage,and skeletal muscle
应用类型
Western blotting (0.5-4 ug/ml), immunoprecipitation, and Immunohistochemistry. However, the optimal conditions should be determined individually. Detects 43 kDa cathepsin K of human, mouse, and rat origin.
免疫原
Synthetic peptide surrounding amino acid 321 of rat cathepsin K
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的Cathepsin K 蛋白发生免疫反应.
保存建议
提供的Cathepsin K 抗体产品为100 ug 无色溶液,其浓度为0.2 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该Cathepsin K 抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.