BI-1 (Bax inhibitor-1),also designated TEGT for testis enhanced gene transcript,was identified as an additional inhibitor of apoptosis. BI-1 interacts with Bcl-2 and Bcl-xL,but not with Bax or Bak,to inhibit Bax induced apoptosis.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects BI-1 in samples from mouse, rat and human origins.
免疫原
Synthetic peptide corresponding to residues around amino acids 210 of human BI-1