p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by reagents (e.g.,ultraviolet and g-irradiation) that can cause DNA damages and then functions in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression.
应用类型
Western blot
免疫原
Synthetic peptide corresponding to amino acids near the N-terminus of human p53R2.