AKT3 is a member of the AKT,also called PKB,serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation,differentiation,apoptosis,tumorigenesis,as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF),insulin,and insulin-like growth factor 1 (IGF1).
应用类型
The antibody can be used for ELISA (0.25 ug/ml) and Western Blotting (2.5 – 5.0 ug/ml).
免疫原
Synthetic peptide corresponding to amino acids surrounding T447 of human Akt3
来源宿主
兔
反应性
经检测验证,可与人、小鼠种属来源的Akt3蛋白发生免疫反应.
保存建议
提供的Akt3抗体产品为100 ug 无色溶液,其浓度为0.25 mg/ml,溶解于包含有0.09% (W/V) 叠氮钠的PBS缓冲液中.请将该Akt3抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.