AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore,AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
应用类型
The antibody can be used for ELISA (0.25 ug/ml) and Western Blotting (0.5 – 2.5 ug/ml).
免疫原
Synthetic peptide selected from the C-terminal region of human Akt2
来源宿主
兔
反应性
经检测验证,可与人种属来源的Akt2蛋白发生免疫反应.
保存建议
提供的Akt2抗体产品为100 ug 无色溶液,其浓度为0.25 mg/ml,溶解于包含有0.09% (W/V) 叠氮钠的PBS缓冲液中.请将该Akt2抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.