HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes,including hepatocyte nuclear factor 1 alpha,a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver,kidney,and intestines. Mutations in this protein have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
应用类型
The antibody can be used for ELISA (0.25 ug/ml) and Western blotting (2.5 – 5.0 ug/ml).
免疫原
Synthetic peptide corresponding to the amino acid residues surrounding S142 of human HNF4A
来源宿主
兔
反应性
经检测验证,可与人种属来源的HNF4A蛋白发生免疫反应.
保存建议
提供的HNF4A抗体产品为100 ug 无色溶液,其浓度为0.25 mg/ml,溶解于包含有0.09% (W/V) 叠氮钠的PBS缓冲液中.请将该HNF4A抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.