AMPK (PRKAA1) belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5’-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
应用类型
The antibody can be used for ELISA (0.25 ug/ml), Western blotting (2.5 – 5.0 ug/ml) and Immunohistochemistry (5 -25 ug/ml).
免疫原
Synthetic peptide corresponding to the amino acid residues surrounding S487 of human PRKAA1
来源宿主
兔
反应性
经检测验证,可与人种属来源的AMPK蛋白发生免疫反应.
保存建议
提供的AMPK抗体产品为100 ug 无色溶液,其浓度为0.25 mg/ml,溶解于包含有0.09% (W/V) 叠氮钠的PBS缓冲液中.请将该AMPK抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.