Cytochrome P450 is mainly found in liver,and can metabolize a wide range of compounds such as organic solvents,acetaminophen,dimethylnitrosoamine and aliphatic alcohol,which have certain toxicological effects in humans. Ethanol-induced cytochrome P450 IIE1 is considered to be one of the major causes of oxidative stress in the liver following ethanol treatment.
应用类型
Western blotting (0.5-4 ug/ml) .However, the optimal conditions should be determined individually. The antibody detects ~58kDa cytochrome P450 IIE1 from samples of human, mouse, rat and dog origins.
免疫原
Synthetic peptide surrounding amino acid 405 of human Cytochrome p450
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠、狗种属来源的Cytochrome P450蛋白发生免疫反应.
保存建议
提供的Cytochrome P450抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Cytochrome P450抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.