中文名称

Lipid A Monophosphoryl, Salmonella minnesota R595

英文名字

Lipid A Monophosphoryl, Salmonella minnesota R595

供应商

USBiological

产品货号

215944

产品报价

￥1/1mg

产品说明书

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购买方式

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产品新闻

背景资料

USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！

产品描述

Lipopolysaccharide (LPS) structures may be generally described as three linked regions. The first structural feature is the lipid component Lipid A, primarily responsible for the effects of endotoxin. Linked to Lipid A is the core antigen or R polysaccharide, a short chain of sugars including 2-keto 3-deoxyoctonate (KDO). The third structural feature is attached to the core polysaccharide and is more elaborate, containing up to 40 repeating subunits of 3 to 5 sugars, referred to as the O antigen, O side chain or O polysaccharide. Variations in the composition of the O antigen account for the species specific antibody responses. Lipid A, acting alone or as a component of LPS, is a potent modulator of the mammalian immune response.  The presence of Lipid A or LPS in mammalian macrophages or endothelial cells triggers a signaling cascade leading to the secretion of pro-inflammatory cytokines and nitric oxide. LPS also acts as a B cell mitogen. Differences in Lipid A fatty acid side chain structures may be responsible for variations of the known effects on the immune system. Source: Lipid A Monophosphoryl from Salmonella minnesota R595Analysis:2-Keto-3-deoxyoctonate (KDO)- 0.027% Phosphate- 3.4% Activity:The hydrolysis conditions employed here yield a preparation which, as assessed by thin layer chromatography and phosphate analysis, is primarily monophosphoryl lipid A (i.e., the glucosamine-1-phosphate group is no longer present and only the glucosamine-4'-phosphate remains). This product, therefore, would be expected to be mitogenic but considerably less toxic than its parent LPS or a diphosphoryl lipid A preparation that is prepared using milder hydrolysis conditions and in which the glucosamine-1-phosphate group is still present.Reconstitution:This product is provided as a lyophilized powder, sealed under vacuum. Lipid A is insoluble in water. It may be suspended in DMSO or 0.5% triethylamine. A usable suspension may also be achieved in water by heating at 50°C combined with intermittent vortexing and/or sonication. This product should be stored at 4°C prior to and following reconstitution. Storage and Stability:Lyophilized powder may be stored at 4°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at 4°C. Reconstituted product is stable for 6 months at 4°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

产品形式

该产品为冻干粉形式。 No preservative added，缓冲液为：DMSO or 0.5% triethylamine。 Handle Gently。Do not vortex。

保存建议

接收到Lipid A Monophosphoryl, Salmonella minnesota R595产品后，置于4°C Do Not Freeze温度下保存。

其他

Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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