- 中文名称
Nerve Growth Factor Receptor, Fc Chimera, Human (Low-affinity Nerve Growth Factor Receptor, NGF Receptor, Gp80-LNGFR, p75 ICD, Low Affinity Neurotrophin Receptor p75NTR, p75NTR, CD271)
- 英文名字
- Nerve Growth Factor Receptor, Fc Chimera, Human (Low-affinity Nerve Growth Factor Receptor, NGF Receptor, Gp80-LNGFR, p75 ICD, Low Affinity Neurotrophin Receptor p75NTR, p75NTR, CD271)
- 供应商
- USBiological
- 产品货号
- 215380
- 产品报价
- ￥1/25ug
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- Nerve growth factor (NGF) receptor, also known as p75NTR, is a low affinity NGF receptor. It binds with equal affinity neurotrophins such as beta NGF, BDNF, NT-3 and NT-4. NGF receptors mediate signaling of neurotrophins for neuronal survival, apoptosis, neurite outgrowth and synaptic plasticity. These receptors are also thought to play a role in neurogenerative diseases such as Alzheimers disease. The NGF receptor is a type I transmembrane glycoprotein (399aa) consisting of a signal peptide (28aa), an extracellular domain (222aa) which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain (22aa) and a cytoplasmic domain (155aa).Source:Nerve Growth Factor Receptor-Fc Chimera, from human DNA sequence encoding the signal peptide and extracellular domain of human NGF receptor aa1-250 was fused to the Fc region of human IgG1 aa93-330. The chimeric protein was expressed in modified human 293 cells.Molecular Weight:~75kD-100kD with post-translational modification and ~50.8kD unmodified.Biological Activity:The ED50 of the NGF Receptor-Fc chimera is typically 0.7-1ug/ml as measured by its ability to neutralize beta NGF mediated proliferation of the human growth- factor dependent TF-1 cell line.Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- 产品形式
- 该产品为冻干粉形式，缓冲液为：500ul PBS。
- 保存建议
- 接收到Nerve Growth Factor Receptor, Fc Chimera, Human (Low-affinity Nerve Growth Factor Receptor, NGF Receptor, Gp80-LNGFR, p75 ICD, Low Affinity Neurotrophin Receptor p75NTR, p75NTR, CD271)产品后，置于-20°C温度下保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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