Complement C1q, Human (Adipocyte Complement-related Protein of 30kD, AdipoQ, APM1, Adiponectin, Gelatin Binding Protein 28kD, GBP28, Adipocyte Most Abundant Gene Transcript)-Complement C1q, Human (Adipocyte Complement-related Protein of 30kD, AdipoQ, APM1, Adiponectin, Gelatin Binding Protein 28kD, GBP28, Adipocyte Most Abundant Gene Transcript)-生化试剂-艾美捷科技有限公司

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中文名称: Complement C1q, Human (Adipocyte Complement-related Protein of 30kD, AdipoQ, APM1, Adiponectin, Gelatin Binding Protein 28kD, GBP28, Adipocyte Most Abundant Gene Transcript)

英文名字: Complement C1q, Human (Adipocyte Complement-related Protein of 30kD, AdipoQ, APM1, Adiponectin, Gelatin Binding Protein 28kD, GBP28, Adipocyte Most Abundant Gene Transcript)

供应商: USBiological

产品货号: 208805

产品报价: ￥1/100ug

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背景资料: USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！

产品描述: Adipose tissue is the largest reservoir of fuel, storing energy in the form of rapidly utilizable triglycerides. Adipocytes synthesize and store energy in periods of nutritional abundance and mobilize lipids during starvation and other times of need. The switch from energy storage to expenditure is finely regulated by a variety of hormones. In order to accomplish these complex tasks energy balance, adipocytes express many genes, including adipsin, involved in lipid metabolism and glucose homeostasis. Many of these genes are finely regulated during adipocyte differentiation and maturation. Several adipocyte-derived proteins act in an autocrine or paracrine fashion to control its own and other cell's cellular physiology.Acrp30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, Acrp30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans, and low levels are associated with insulin-resistance. C1q is serum glycoprotein of 18-polypeptides chains consisting of three non-identical subunits, A (29kD), B (26kD), and C (246aa, 19kD) in molar ratio of 1:2:2. C1Q in the plasma is complexed with two proenzymes C1r and two C1s molecule to form the first component of complement (C1). Activation of complement via classical pathway is triggered by binding of globular head of C1q to immune complexes containing IgG (Fc-region) or IgM or to a variety of other activating substances, including C-reactive protein, retrovirus, and mitochondria. Subsequent to C1q binding, c1r and C1s are converted to proteolytic enzymes that are responsible to continuation of activation via the classical pathway.Source:C1q, from human serumApplications: Suitable for use in ELISA and Western Blot. Other applications not tested.Recommended Dilution:ELISA: Native ~410kDWestern Blot: 1:10-50K; 10-100ng of control peptide/wellOptimal dilutions to be determined by the researcher.Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

产品形式: 该产品为液体形式，缓冲液为：PBS, pH 7.4。No preservative added。

保存建议: 接收到Complement C1q, Human (Adipocyte Complement-related Protein of 30kD, AdipoQ, APM1, Adiponectin, Gelatin Binding Protein 28kD, GBP28, Adipocyte Most Abundant Gene Transcript)产品后，置于-20°C温度下保存。

其他: Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。