- 中文名称
DMH1
- 英文名字
- DMH1
- 供应商
- Cayman Chemical
- 产品货号
- 16679-5
- 产品报价
- ¥询价/5mg
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Bone morphogenetic proteins (BMP) are secreted signaling proteins, many of which are involved in various developmental processes, in addition to bone formation.{23503} DMH1 is an analog of the non-selective BMP receptor inhibitor dorsomorphin (Item No. 11967) that potently inhibits the kinase activity of activin receptor-like kinase 2 (ALK2; IC50 = 13-108 nM).{28912,28826} It is much less effective at ALK4, ALK5, AMPK, KDR (VEGFR2) or PDGFRβ, although it inhibits ALK1 and ALK3 at nanomolar concentrations.{28912,28826} DMH1 is effective in vivo, as it disrupts dorsoventral development in zebrafish.{28912} It also affects stem cell development, increasing cardiomyocyte progenitors and promoting neurogenesis.{28911,28914} DMH1 inhibits the growth of lung cancer cells, reducing tumor growth in a xenograft mouse model.{28913}
- 产品描述
- A potent inhibitor of the kinase activity of ALK2 (IC50 = 13-108 nM); disrupts dorsoventral development in zebrafish; affects stem cell development, increasing cardiomyocyte progenitors and promoting neurogenesis; inhibits the growth of lung cancer cells, reducing tumor growth in a xenograft model
- 产品形式
- 晶体
- 保存建议
- 建议您在收到Cayman Chemical品牌的DMH1 (5 mg)产品后置于-20℃保存.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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