Bupivacaine is an amino-amide anesthetic that binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, preventing the generation of an action potential.{27206} At 100 ?M, it has been reported to inhibit the uptake of dopamine in striatal synaptosomes by 47%.{24176}
产品描述
An amino-amide anesthetic that binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, preventing the generation of an action potential; inhibits the uptake of dopamine in striatal synaptosomes by 47% at 100 ?M