中文名称

7-氧代胆固醇| SC-4722 |Δ5-胆固醇-3β-ol-7-one；3β-hydroxy-cholest-5-en-7-one

英文名字

7-oxo Cholesterol|SC-4722|Δ5-Cholesterol-3β-ol-7-one; 3β-hydroxy-cholest-5-en-7-one

供应商

Cayman Chemical

产品货号

16339-10

产品报价

￥询价/10mg

产品说明书

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购买方式

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产品新闻

背景资料

7-keto Cholesterol is a bioactive sterol that can affect cholesterol homeostasis, membrane properties and cell survival.{26766,26765} It strongly inhibits cytochrome P450 7A1 (CYP7A1), the cholesterol 7α-hydroxylase, with an IC50 = ~ 1 µM.{26765} 7-keto Cholesterol can be produced by oxidation of cholesterol associated with ethanol-mediated lipid peroxidation or photodamage.{26762,26763,26764} It can also be derived enzymatically by oxidation of 7-dehydrocholesterol, the immediate precursor of cholesterol, by CYP7A1, while 11β-hydroxysteroid dehydrogenase type 1 stimulates its reduction.{26765,26761} 7-keto Cholesterol is a major oxysterol component of oxidized LDL.{26766,5829} This compound can be used as a standard in the determination of cholesterol derivatives by GC-MS or HPLC.

产品描述

A bioactive sterol that can affect cholesterol homeostasis, membrane properties and cell survival; inhibits CYP7A1 with an IC50 = ~ 1 µM; can be used as a standard in the determination of cholesterol derivatives by GC-MS or HPLC

产品形式

A crystalline solid

保存建议

建议您在收到Cayman Chemical品牌的7-keto Cholesterol (10 mg)产品后置于-20度保存，产品有效期为730天.

其他

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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