CP-690550(25毫克)产品是CP-690550 treatment of murine factor-dependent cell Patersen-erythropoietin receptor (FDCP-EpoR) cells harboring human wild-type or V617F JAK2 resulted in inhibition of cell proliferation with an IC₅₀ of 2.1 uM and 0.25 uM, respectively. Furthermore, CP-690550 treatment of ex-vivo-expanded erythroid progenitors from JAK2(V617F)-positive PV patients resulted in specific, antiproliferative (IC₅₀ = 0.2 uM) and pro-apoptotic activity.