Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function.{26269} It intercalates into DNA and, when activated by ultraviolet radiation, can create covalent interstrand crosslinks, inducing apoptosis.{26270} Because of its high UV absorbance, psoralen has been combined with UVA light (PUVA therapy) for the treatment of skins problems such as psoriasis.{26268}
产品描述
A photoactive probe that has been used to investigate nucleic acid structure and function; induces DNA interstrand crosslinks, resulting in apoptosis