- 中文名称
Bioperine | N-哌啶基哌啶| NSC 21727；（2E，4E）-5-（1,3-苯并二恶唑-5-基）-1-（1-哌啶基）-2,4-戊二烯-1-酮
- 英文名字
- Bioperine|N-Piperoylpiperidin|NSC 21727; (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one
- 供应商
- 开曼生物
- 产品货号
- 11750-10
- 产品报价
- ￥1/50mg
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Piperine is a natural alkaloid that can be isolated from black pepper. It activates transient receptor potential vanilloid type 1 receptor (TRPV1; EC50 = 38 ?M) and modulates GABAA receptors (EC50s = 43-60 ?M).{27597,27596} At similar levels, piperine inhibits both monoamine oxidases (MAOs), with IC50 values of 21 and 7 ?M for MAO-A and MAO-B, respectively.{27595} Like other natural compounds containing methylenedioxyphenyl substituents, piperine affects cytochrome P450 (CYP) isoforms, inhibiting CYP3A species (Ki ~ 5 ?M) and increasing expression of CYP1A and CYP2B in liver.{25115} It also has a biphasic effect on P-glycoprotein activity.{25373}
- 产品描述
- A natural alkaloid that activates TRPV1 (EC50 = 38 ?M) and modulates GABAA receptors (EC50s = 43-60 ?M); inhibits MAOs (IC50s = 21 and 7 ?M for MAO-A and MAO-B, respectively; inhibits CYP3A species (Ki ~ 5 ?M) and increases expression of CYP1A and CYP2B in liver
- 保存建议
- 其他
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
-
