- 中文名称
抗15-脂肪氧合酶-2多克隆抗体
- 英文名字
- 15-Lipoxygenase-2 Polyclonal Antibody
- 供应商
- Cayman
- 产品货号
- 10004454-500
- 产品报价
- ￥3206/500 μl
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Two types of 15-LO have been discovered and characterized, both of which metabolize arachidonic acid -AA) to produce 15-S)-hydroxyeicosatetraenoic acid -15-S)-HETE). 15-LO-1 oxygenates AA at both C15 and C12, whereas 15-LO-2 exclusively oxygenates C15 of AA. Human 15-LO-2 has a molecular mass of approximately 76 kDa and exhibits approximately 40% identity to the reticulocyte 15-LO-1. Expression of 15-LO-2 appears to be restricted to prostate, lung, skin, and cornea and may play a role in the normal development of these tissues. The protein levels and enzymatic activity of 15-LO-2 are both down-regulated in prostate cancer compared with normal and benign prostate tissues, implicating a possible protective role for 15-LO-2 against tumor formation. Cayman Chemical s 15-LO-2 polyclonal antibody can be used for western blot analysis for 15-LO-2 on samples of human origin. Other applications for use of this antibody have not yet been tested.
- 应用类型
- WB
- 免疫原
- human 15-lipoxygenase-2 -15-LO-2) amino acids 161-179 -CLDEKTVEDLELNIKYSTA)
- 来源宿主
- rabbit
- 反应性
- 15-Lipoxygenase-2 -human recombinant)+|15-Lipoxygenase-1 -rabbit reticulocyte)-|12-Lipoxygenase-1 -porcine leukocytes)-|Human 5-Lipoxygenase-
- 保存建议
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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