Defined substructure of the Re mutant of lipopolysaccharide (LPS). Strong activator (<10ng/ml) of toll-like receptor 4 (TLR4). Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice. No further re-extraction required. Isolated and purified from E. coli K12 heptose-deficient strain WBB06 (Re mutant) [1] by a modification of the PCP extraction method [2,3], converted to the uniform sodium salt form [4] and dissolved in sterile pyrogen-free double distilled water. Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
产品形式
该产品为液体,缓冲液为:pyrogen-free double distilled water。
保存建议
接收到Kdo2-Lipid A ((3-Deoxy-D-manno-octulosonic acid)2-Lipid A)产品后,置于4°C温度下保存。